Thursday, February 20, 2014


As it passes, time leaves traces...
Aging is a gradual process, affecting slowly our entire body. One of the areas revealing the biological age is the face. First, fine lines appear on the forehead, around the eyes and around the mouth, deepening as years go by. In early stages, wrinkles form only when the face moves - smiling, loughing, yawning, grimaces. In this stage, they are called dynamic wrinkles or expression lines. Slowly, the dynamic wrinkles convert to static wrinkles, becoming visible also when the face does not move.
In order to treat dynamic wrinkles and to stop their convertion into static wrinkles, we need a substance that is able to relax mimics muscles. The most known product, used all over the world , is Botox - Botullinum Toxin.
Nowadays, we have an alternative - Argireline, an anti-wrinkle solution that combines two active ingredients (Acetyl Hexapeptide-3 and Leuphasyl) to achieve a mild, safe, non-toxic botox-like effect, reducing and preventing 'emotional' wrinkles by inhibiting muscle contraction. It is the perfect option for those persons who do not want to lose their full range facial expression.

How does Argireline work?
Argireline has been proven to be effective both in reducing existing facial wrinkles and in preventing formation of new ones; it is effective in treating expression lines on the forehead, glabela (between the eyebrows), crow's feet (the outer corner of the eyes) and the 'bar code' lines on the upper lip.
As mentioned above, Argireline is a combination of 2 substances. Acetyl Hexapeptide-3 is a succession of amino acids that form a chain. The peptides have the ability to influence the function of skin cells, inducing collagen synthesis. The result of this action is maintenance of skin elasticity and prevention of  new wrinkle formation. Leuphasyl, a pentapeptide , mimics the natural path of the enkephalins, it acts on formation of expression lines in a new way. It actually is a modified enkephalin linking to the enkephalin receptors, outside the nervous cells.

In addition, Argireline intervenes in the biochemical course of the muscular contraction, interfering with the action of the neurotransmitters. The result is the relaxation of the facial muscles involved in the mimics of the face and again, the prevention of dynamic wrinkles formation.

Argireline can be utilized by topical application - there are numerous cremes and facial serums containing Argireline worldwide. A study published in the International Journal of Cosmetic Science demonstrated that expression lines decreased with 30 % after topical application of Argireline during a period of 30 days.
I prefer using the active ingredient per se - my methods of choice are conventional or no needle mesotherapy. Of course, Dermaroller and Derma Pen can also be used.

Benefits of Argireline
It is a safe, non toxic ingredient. It does not affect facial expression. And also to be considered, it is a relatively cheap solution for removing expression lines.
The duration of the effects depends on the treatment we choose. If injected, the effects of Argireline can last 4-6 months, depending on the patient's age, on the skin elasticity, on the depth of the lines.

Argireline defies the time!


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  2. Nice blog.
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